This will be a massive result for the team that had already knocked Roma out of the Coppa Italia.
The Giallorossi came into the match off a confident Europa League play-off win against RB Salzburg. Knowing that a win would put them on level with Inter and Milan, they lost the opportunity.
This is a shocking win for a team that had failed to record a single win in the league but had knocked Napoli and Roma out of the Coppa Italia to reach the semi-finals.
The first chance of the game came to Roma’s way as Paulo Dybala’s back-heel flick released Wijnaldum to flash a shot across the face of the goal from a tricky angle.
Felix Afena-Gyan also blasted his shot over from distance against his old club.
They later went into the lead through Frank Tsadjout. Emanuele Valeri used his chest to cushion a ball over the top, while Tsadjout, who let it bounce, smashed on the half-volley into the roof of the net from the edge of the box.
They held on to the lead in the first half to break a record set since facing Bari on April 19, 1996.
A few minutes into the second half, Jose Mourinho was sent off for dissent.
The hosts were looking for the killer blow and fully concentrated as Marco Carnesecchi was alert to anticipate Lorenzo Pellegrini first, then Andrea Belotti. Cremonese also attempted to score a second on the counter with three against three.
After making a quadruple substitution on the hour, Roma had some chances to equalize. Ferrari charged Stephan El Shaaraha’s two shots in quick succession.
The Giallorossi will eventually restore parity with their first shot on target. It was a magnificent moment of football for Mourinho’s men.
Mancini floated a long ball over the top to Spinazzola, who timed his run perfectly to spring the offside trap. He had a sublime first touch and kept his cool to sweep it into the bottom corner.
The goal boosted Roma’s confidence as they suddenly burst to life.
Dybala’s shot was straight at the goalkeeper, and Carnesecchi rushed off his line and fingertip the ball off the foot of El Shaarawy, who was clear on goal.
However, the host eventually got the second goal and the winner from the penalty spot. Daniel Ciofani’s deflected shot turned into an assist for David Okereke, who was brought down by on-rushing Rui Patricio
Although the goalkeeper picked the right angle, Ciofani drilled the spot-kick right into the bottom corner to secure their first Serie A win of the season.