Everton manager Ronald Koeman has admitted that winger Yannick Bolasie could be out for up to a year in total.
Bolasie was brought off during the 1-1 draw and underwent knee surgery last month to rectify the issue.
The 27-year-old is due to have a second operation in the coming weeks and Koeman says he will be out for a “long time”.
Speaking at the club’s Annual General Meeting, the Dutchman said: “It is a long-term injury – 10, 11, 12 months. He will come back, he has a strong mentality.”
Although Bolasie has played a key role for the Toffees this season, Everton have won three of their last six matches since he suffered his injury.
The likes of Aaron Lennon, Tom Cleverley, Tom Davies, Gerard Deulofeu and Kevin Mirallas have stepped up to help the club climb the table.
Everton sit seventh in the Premier League table and Koeman is expected to bring in another winger in the January transfer window.
Charlton youngster Ademola Lookman is set to move to Goodison Park in the next few days.
Everton face Leicester in the third round of the FA Cup this weekend and are 1.85 favourites to win the game.