Wales boss Ryan Giggs faces a selection dilemma in defence after Neil Taylor was forced to pull out of the squad through injury.
The Welsh host Denmark on Friday in Cardiff in the Nations League and then travel to Albania on November 20 for a friendly.
Left-back Taylor had to be removed from the action with an injury at half-time in club side Aston Villa’s 3-0 Championship win at Derby on Saturday and has failed to recover in time.
Giggs is already without fellow left-back Ben Davies but is yet to call up a replacement for Taylor.
Taylor, 29, has been capped 41 times by Wales but is yet to feature since Giggs took charge. Brentford defender Chris Mepham has already been ruled out of the squad, with Kieron Freeman of Sheffield United called up as his replacement.
Wales know a win in Cardiff would see them top Group B and secure promotion to League A, while defeat would see the Danes move to the top of the standings.
Wales are 2.70 to win and Aaron Ramsey is 9.50 to score the first goal in Cardiff. A win for Denmark is available at 2.80 and the draw is 3.00.
Denmark won the reverse fixture 2-0 in September thanks to two goals from Tottenham star Christian Eriksen and he can be backed at 3.50 to score anytime on Friday night.